Pair Name | Vitamin C, Lenvatinib | ||
Phytochemical Name | Vitamin C (PubChem CID: 54670067 ) | ||
Anticancer drug Name | Lenvatinib (PubChem CID: 9823820 ) | ||
Structure of Phytochemical |
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2D
MOL
3D
MOL
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Structure of Anticancer Drug |
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2D
MOL
3D
MOL
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Pair Name | Vitamin C, Lenvatinib | |||
Disease Info | [ICD-11: 2C12] | Hepatocellular carcinoma | Investigative | |
Biological Phenomena | Inhibition-->Cell proliferative, migratory and invasive capacities | |||
Gene Regulation | Down-regulation | Expression | MET | hsa4233 |
In Vitro Model | Hep 3B2.1-7 | Childhood hepatocellular carcinoma | Homo sapiens (Human) | CVCL_0326 |
Huh-7 | Adult hepatocellular carcinoma | Homo sapiens (Human) | CVCL_0336 | |
SK-HEP-1 | Liver and intrahepatic bile duct epithelial neoplasm | Homo sapiens (Human) | CVCL_0525 | |
Result | Combination of Vitamin C and Lenvatinib potentiates antitumor effects in hepatocellular carcinoma cells in vitro |
No. | Title | Href |
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1 | Combination of Vitamin C and Lenvatinib potentiates antitumor effects in hepatocellular carcinoma cells in vitro. PeerJ. 2023 Jan 25;11:e14610. doi: 10.7717/peerj.14610. | Click |